Placebo interventions, placebo effects and clinical practice
نویسندگان
چکیده
منابع مشابه
Placebo interventions, placebo effects and clinical practice.
This article reviews the role of placebo interventions and placebo effects in clinical practice. We first describe the relevance of different perspectives among scientists, physicians and patients on what is considered a placebo intervention in clinical practice. We then summarize how placebo effects have been investigated in randomized controlled trials under the questionable premise that such...
متن کاملPlacebo interventions for all clinical conditions.
BACKGROUND Placebo interventions are often claimed to improve patient-reported and observer-reported outcomes, but this belief is not based on evidence from randomised trials that compare placebo with no treatment. OBJECTIVES To assess the effect of placebo interventions. SEARCH STRATEGY We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 4, ...
متن کاملUsing the placebo response in clinical practice.
This paper reviews the psychological mechanisms that lead to placebo responses and the physiological basis for reduction in symptoms. Some psychological mechanisms (expectancy, conditioning) lead to symptom reduction but are unlikely to reduce underlying pathology. Other mechanisms (therapeutic relationship, empowerment) may additionally reduce later pathology. The nature, size and duration of ...
متن کاملPlacebo effects: clinical aspects and neurobiology.
Placebo effects are beneficial health outcomes not related to the relatively direct biological effects of an intervention and can be elicited by an agent that, by itself, is inert. Understanding these placebo effects will help to improve clinical trial design, especially for interventions such as surgery, CNS-active drugs and behavioural interventions which are often non-blinded. A literature r...
متن کاملPlacebo Effects
A placebo is a treatment that is expected to have no inherent pharmacological or physical benefit — for instance, a starch capsule given for anxiety or pain, or sham surgery in which the critical surgical procedure is not performed. Placebos are often used for comparison in clinical studies, as a baseline against which to evaluate the efficacy of investigational clinical treatments. However, pl...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society B: Biological Sciences
سال: 2011
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2010.0383